Sleep Quality & Memory Retention

In addition to blood pressure reduction to calm anxiety in getting to sleep, improved sleep from grapes, one time attributed to melatonin, have shown positive sleep and memory benefits directly from a diet with grape polyphenols.

Supporting Research (Sleep & Memory)

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A higher dietary intake of certain polyphenols found in grapes and other Mediterranean fruits and vegetables have associations with better sleep quality among adult individuals as reported in a 2020 study of 1936 Italian adults (Nutrients . 2020 Apr 26;12(5):1226. https://pubmed.ncbi.nlm.nih.gov/32357534/).  Studies have shown that bioactive dietary polyphenol preparations (BDPP) made from grapes resisted memory loss from sleep deprivation (Neurochemistry International. 2015 Oct; 89:191-197. https://www.sciencedirect.com/science/article/abs/pii/S0197018615300255).  The mechanisms of improved memory retention and better sleep quality involve the promotion of protein translation in the hippocampus.  (FASEB. 2018 Oct; 32(10): 5390-5404https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201800030R).